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CANM will bring together thirteen researchers from three different campuses and four different departments to work on research projects relevant to NASA in collaboration with NASA Glenn Research Center (GRC), NASA Ames Research Center (ARC), and Jet Propulsion Laboratory (JPL), in areas that correspond primarily to the Exploration Systems Mission Directorate and secondarily to the Aeronautics Research Mission Directorate.

Other national partners include the Cornell Center for Materials Research (CCMR) and University of Massachusetts at Amherst Center for Hierarchical Manufacturing (UMass CHM). At the Jurisdiction level, CANM will partner with PR NASA EPSCoR, PR NASA Space Grant, the PR Institute for Functional Nanomaterials (IFN), the PR Small Business & Technology Development Centers (SBTDC), and the PR Industrial Development Company (PRIDCO).